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Molecular Medicine Peer-reviewed scientific journal

Molecular Medicine

ASSOCIATIONS OF SINGLE NUCLEOTIDE POLYMORPHISMSWITH BONE TUMORS IN PATIENTS IN RUSSIAN POPULATION

Kushlinskii N.E., Timofeev Yu.S., Generozov E.V., Naumov V.A., Soloviev Yu.N., Boulytcheva I.V.

Authors and affiliations

N.E. Kushlinskii (1), Yu.S. Timofeev (1), E.V. Generozov (2), V.A. Naumov (2), Yu.N. Soloviev (1), I.V. Boulytcheva (1)
1 - Federal State Budgetary Institution «The N.N. Blokhin Russian Cancer Research Center» of the Russian Academy of Medical Sciences, Moscow, Russian federation; 2 -Federal State Institution «Scientific Research Institute of Physicochemical medicine» of the Federal Medical – Biological Agency (FMBA) of Russia

Published
2013

Abstract

Ethiology and pathogenesis of bone tumors presenting a rare group of oncological diseases, are not fully understood. We have studied
6 single nucleotide polymorphisms rs7921 (GH1), rs7956547(IGF1), rs3761243(GNRH2), rs11737764(FGF2), rs6599400(FGFR3),
rs1690916(MDM2) associations with bone tumors in Russian patients. In our work we detect associations between 3 single nucleotide
polymorphisms: IGF1.rs7956547, GNRH2.rs3761243 and FGFR3.rs6599400 in patients with bone tumors.

Keywords

Authors and affiliations

N.E. Kushlinskii (1), Yu.S. Timofeev (1), E.V. Generozov (2), V.A. Naumov (2), Yu.N. Soloviev (1), I.V. Boulytcheva (1)
1 - Federal State Budgetary Institution «The N.N. Blokhin Russian Cancer Research Center» of the Russian Academy of Medical Sciences, Moscow, Russian federation; 2 -Federal State Institution «Scientific Research Institute of Physicochemical medicine» of the Federal Medical – Biological Agency (FMBA) of Russia

How to cite

Kushlinskii N.E., Timofeev Yu.S., Generozov E.V., Naumov V.A., Soloviev Yu.N., Boulytcheva I.V. (2013). ASSOCIATIONS OF SINGLE NUCLEOTIDE POLYMORPHISMSWITH BONE TUMORS IN PATIENTS IN RUSSIAN POPULATION. Molecular Medicine, (1).

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