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Molecular Medicine
Found: 72
Introduction. One of the actual task of modern biology and medicine is the creation of bioregulator preparation, which have the stimulating effect on the organs of genitourinary system. Purpose of study. Study of stimulating effect on cellular proliferation of…
Introduction. The liver serves as a buffer for the accumulation and utilization of excess intake of nutritional fats, the intake of plant compounds can improve metabolic processes in the liver, but the molecular mechanisms of this phenomenon have been little s…
Introduction. Autoimmune oophoritis is one of the causes of premature ovarian insufficiency in 3–40% of cases. Representative diagnosis is possible only through histological examination of ovarian biopsy material, which complicates the identification of early …
Introduction. One of the actual task of modern biology and medicine is the creation of bioregulator preparation, which have the proliferotropic effect on the internal organs of organism. Purpose of study. Study of proliferotropic effect of short peptides and p…
Introduction. Additionally to electrophysiological and clinical methods the neurofilament light chains (Nf-L) concentration in blood plasma is considered as a marker for predicting functional outcomes. The aim of the study. Assessment of neurofilament light ch…
Introduction. Sarcoidosis is a systemic granulomatous disease of unknown origin. The study of its features and the development of new diagnostic and treatment methods are limited by the absence of generally accepted experimental models. The purpose of the revi…
Introduction. Ionizing radiation can lead to radiation damage to healthy pancreatic tissue, with the development of signs of post-radiation pancreatitis. Electron irradiation potentially has the most “sparing” effect on healthy tissue, but data on this are spa…
Introduction. One of the actual task of modern biology and medicine. Is the creation of bioregulator preparation, which can stimulate the neuroendocrine system of organism. Purpose of study. Study of effect of polypeptide complex from brain cortex (PPCbc) and …
Introduction. An urgent problem in biology and medicine is the identification of biologically active molecules that affect the cellular processes of proliferation and apoptosis in various tissues of the body. Purpose of the study. The purpose of this study was…
Introduction. Hyperglycemia inducers, the «classic» diabetogens streptozotocin and alloxan have a pronounced effect and are therefore limited suitable for modeling mild hyperglycemia in an experiment. Tyloxapol (Triton WR1339) was chosen as an alternative agen…
Studies of post-radiation lesions of the pancreas after irradiation with charged particles (electrons, protons) are few, however, electron therapy is one of the promising methods in radiobiology and can be used to model post-radiation pancreatitis. The mechani…
Introduction. Thyroid disease is currently the most common among endocrine pathology. Hyperproduction of thyroid hormones is accompanied by stimulation of humoral reactions, contributing to the development of immune-mediated pathology under certain conditions,…
Introduction. Immobilization stress leads to the intensification of free-radical reactions leading to the destruction of sialoglycoproteins of the gastroduodenal zone. The aim of the study. To evaluate the features of the metabolism of sialoglycoproteins in th…
Introduction. To date, the problem of studying the neuropeptide system of regulation of adaptive processes is relevant, since the stress reaction is a trigger for the occurrence of various diseases, in particular depression. Corticoliberin is considered as the…
Introduction. An urgent problem in biology and medicine is the identification of biologically active molecules that affect the cellular processes of proliferation and apoptosis in various tissues of the body. Purpose of the study. The purpose of this study was…
Introduction. Ischemic stroke is one of the most common causes of mortality and primary disability. The treatment of ischemic stroke, especially its complications, includes neuroprotective agents among which correctors of mitochondrial dysfunction stand out. A…
Introduction: Great progress has been made in the treatment of arterial hypertension (AH). However, despite the fact that new technologies have paved the way for practical medicine, the number of deaths and disabilities from diseases of the cardiovascular syst…
Introduction. The formation of effective bioregulators for the maintenance of the basic physiological functions, so as polypeptide complexes (PPCs), is one of the actual task of modern biology and medicine. Purpose of study. Effect of combination of polypeptid…
Introduction. An experimental study of the pathogenetic mechanisms of the development of inflammatory-destructive changes in the joints in animal models was carried out in order to develop new diagnostic strategies for further implementation of the results obt…
Introduction. Nootropic drugs are used at all stages in treatment of behavioral disorders associated with alcohol consumption, when the correction of the functions of operational (working) memory and attention contributes to a more adequate processing and assi…