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Molecular Medicine
Found: 28
Introduction. The angiogenesis in a uterus scar after application of multipotent mesenchymal stromal cells of a bone marrow origin (MMSCBM) was shown. However, possibility of approach of pregnancy and spontaneous deliveries in rats after MMSCBM introduction in…
Introduction. In interstitial lung diseases (ILD), characterized by inflammatory and fibrous processes, the intensification of angiogenesis also occurs. The aim of our research. Was the study of characteristics of expression angiogenic molecules (VEGF, ET1) in…
Introduction. Determination of the functional activity of the endometrium at the molecular-cellular level opens new perspectives for diagnosis and correction processes of accelerated aging and pathology of the female’s reproductive system. Objective – learning…
The formation of properties promoting malignant transformation begins before the appearance of tumor cells at the level of inflammatory and precancerous processes. The basis for these properties is genomic instability of tumor cells. Genetic instability manife…
Introduction. Activation of eNOS/sGC/cGMP-pathway is a common link in the development of angiogenic action of the majority of pro-angiogenic factors. In this regard, the chemical inhibition of NOS (Nitric Oxide Synthase) may cause a nonspecific angiostatic eff…
Introduction. The one of the most important problems of the modern regenerative medicine is incomplete understanding of the influence of mesenchymal stem cells (MSCs) on the growth of malignant neoplasms. Aim of the study. Analysis of the allogeneic MSCs’ effe…
A literature review is devoted to the analysis of clinical significance of key factors of neoangiogenesis in ovarian cancer patients, their connection with the main clinical and morphological characteristics of the disease, prognosis, features an anti-angiogen…
Abstract: This review summarizes the results of studies devoted to identification the dominant mechanisms of formation and persistence of inflammation in severe asthma. According to the latest research, the most likely causal factors and molecules that underli…