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Molecular Medicine Peer-reviewed scientific journal

Found: 23

Research article2014

EVOLUTIONARY MEDICAL GENOMICS

«Nothing in biomedicine makes sense except in the light of evolution». From this point of view, genetics of predispositions hasto answer two basic questions: 1. Is the natural genetic polymorphism identified with modern genomics proved to be the result of neut…

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Research article2013

ANALYSIS OF GENETIC POLYMORPHISMS IN ESTROGENMETABOLIZING ENZYMES IN OVARIAN CANCER PATIENTS IN THE SIBERIA REGION

Early diagnosis of ovarian cancer (OC) remains to be the actual problem in modern oncology due to the high mortality rate, asymptomatic course of the disease in the early stages and its aggressiveness. The aim was to study the genetic polymorphism of pathogene…

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Research article2013

PLEIOTROPIC EFFECTS OF MULTIFACTORIAL DISEASE SUSCEPTIBILITY GENES

The article provides a brief overview of the evolution of views on the phenomenon of pleiotropy. We discuss with assessment of pleiotropic effects significance in the formation of human pathological states, above all – multifactorial diseases (MFD). Pleiotropi…

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