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Molecular Medicine Peer-reviewed scientific journal

Found: 5

ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2025 · pp. 58–69

Polypragmasy in elderly and senile patients with chronic kidney disease: START/STOP criteria in elderly and senile patients taking DOAC

Introduction. Thanks to the achievements of modern medicine, it was possible to significantly increase the life expectancy of the population. Molecular mechanisms of aging include telomere shortening, DNA damage accumulation, mitochondrial dysfunction, leading…

10.29296/24999490-2025-05-07Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2025 · pp. 39–47

Ways to increase freedom from DOAC-dependent complications in elderly patients with polypharmacy and chronic kidney disease: molecular and genetic aspects

Introduction. Thanks to advances in modern medicine, it has been possible to significantly increase life expectancy. With the high effectiveness of methods for diagnosing and treating many chronic pathologies, a sharp increase in the number of elderly patients…

10.29296/24999490-2025-03-05Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2018

THE CYP2C19*2, CYP2C19*3 POLYMORPHISMS ASSOCIATED WITH THE RESISTANCE TO CLOPIDOGREL IN PATIENTS WITH ACUTE CORONARY SINDROME IN THE YAKUT AND RUSSIAN ETHNIC GROUPS

ntroduction. The aim of this study was to determine the prevalence rate of CYP2C19 alleles, associated with the risk of the resistance to clopidogrel and the development of thrombotic complications in patients with acute coronary syndrome (ACS) from Russian an…

10.29296/24999490-2018-02-08Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2016

MOLECULAR AND CELLULAR FACTORS OF LOCAL IMMUNITY IN ASCITIC FLUID OF OVARIAN CANCER PATIENTS

Introduction. Immunologic microenvironment of malignant tumors is likely to be significant in «tumor-host» interaction. The aim of the study. Сomparative analysis of systemic and local factors of cellular and humoral immunity in patients with ascitic forms of …

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ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2016

RELATIONSHIP OF PLOIDITY AND LOCAL IMMUNITY IN TUMORS OF THE COLON

Introduction. The biologic behaviour of the tumor can be determined by both its own characteristics including ploidity of the tumor cells and peculiarities of its lymphocytic and cytokine microenvironment, in particular. The aim of the study. To perform a comp…

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