Поиск / Search | Molecular medicine

Found: 3

ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2022 · pp. 42–52

ASSOCIATION OF POLYMORPHIC VARIANTS OF NON-ALLELIC GENES ADIPOQ, MTHFR, PON1, KCNJ11, TCF7L2, ITLN1 AND PPARG WITH CLINICAL AND LABORATORY PARAMETERS AMONG OBESE PATIENTS FROM KYRGYZ REPUBLIC

Isakova J.T., Kipen V.N., Aitbaev K.A., Mukeeva S.B., Akynbek kyzy Samara, Mirrakhimov E.M.

Introduction. In Kyrgyzstan about 60% of the adult population suffers from lipid metabolism disorders of varying degrees. Early identification of persons at increased risk of developing obesity is of great importance, which can be achieved through the study of…

10.29296/24999490-2022-05-06Details ↗

ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2019

THE ROLE AND INTERACTION OF POLYMORPHIC VARIANTS OF NON-ALLELIC GENES KCNJ11, ADIPOQ, ITLN1, LEP, TCF7L2, PPARG IN THE INCREASE IN THE RISK OF DIABETES TYPE 2 IN KYRGYZ REPUBLIC

Isakova Zh.T., Kipen V.N., Talaibekova E.T., Aldashev A.A., Aldasheva N.M., Bectursunov T.M., Mirrakhimov E.M.

Aim. To study the intergenic interaction and estimate the contribution of polymorphic loci p.K23E (rs5219, KCNJ11), g.15661G>T (rs1501299, ADIPOQ), p.V109D (rs2274907, ITLN1), g.2453G>A (rs7799039, LEP), g.53341C>T (rs7903146, TCF7L2), and p.P12A (rs1801282, P…

10.29296/24999490-2019-04-06Details ↗

ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2016

G276T ADIPONECTIN GENE POLYMORPHISM IN DEVELOPMENT OF OBESITY AND OBESITY-RELATED DISEASES IN KYRGYZ POPULATION

Isakova Zh.T., Talaibekova E.T., Asambaeva D.A., KerimkulovaA.S., Lunegova O.S., Aldashev A.A.

The aim of this work was to study the relationship between adiponectin gene polymorphisms G276T with obesity and obesity-related diseases in the Kyrgyz population. Material and methods. We genotyped 288 Kyrgyz subjects (143 women and 145 men; age range: 30–75 …

Details ↗