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Molecular Medicine Peer-reviewed scientific journal

Found: 4

ОБЗОР2025 · pp. 16–26

Neurodegenerative diseases as a target for genome editing: from preclinical studies to clinical practice

Objective. To analyze the current state of preclinical and clinical studies in genome editing for neurodegenerative diseases, evaluate its potential impact on clinical practice, and examine ethical aspects of these technologies’ application. Material and metho…

10.29296/24999490-2025-01-02Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2018

QUANTITATIVE DISTRIBUTION OF APOLIPOPROTEIN-E AMONG BLOOD PLASMA LIPOPROTEINS IN HEALTHY MEN

Introduction. Apolipoprotein-E (apoE), being one of the metabolically active apoproteins plays the important role in lipid metabolism. The aim of the study was to investigate the quantitative distribution of apoE between different lipoprotein classes in health…

10.29296/24999490-2018-05-09Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2017

PROTEOMIC AND METABOLOMIC MANIFESTATIONS OF DIFFERENT VARIANTS OF APOLIPOPROTEIN E GENES POLYMORPHISM IN OBESE PATIENTS

Introduction. Currently questions on the role of genes polymorphism that regulate metabolism and implicated in metabolic disorders are disputed. Objective. The study of proteomic and metabolomic manifestations of different variants of apolipoprotein E genes po…

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ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2015

PREDICTION THE RISK OF ISCHEMIC STROKE ON THE BASE ON GENETIC [APOE (Ε2, Ε3, Ε4), ACE (I / D), MTHFR (677S> T)] AND NON-GENETIC FACTORS WITH THE USE OF MODERN METHODS OF THE THEORY OF RECOGNITION BY PRECEDENTS

Introduction. Ischemic stroke (IS) is a multifactorial disease, resulting from a complex interaction of genetic and environmental factors. Individual cause of the disease, multiple factors and symptoms require advanced mathematical methods of predicting IS ris…

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