Found: 4
ОБЗОР2025 · pp. 16–26
Tereshchenko S.Yu., Potupchik T.V., Evert L.S., Alieva L.G., Kozyrina Y.E., Maremkulov A.A.
Objective. To analyze the current state of preclinical and clinical studies in genome editing for neurodegenerative diseases, evaluate its potential impact on clinical practice, and examine ethical aspects of these technologies’ application. Material and metho…
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2018
Kaneva A.M., Potolitsyna N.N., Bojko E.R.
Introduction. Apolipoprotein-E (apoE), being one of the metabolically active apoproteins plays the important role in lipid metabolism. The aim of the study was to investigate the quantitative distribution of apoE between different lipoprotein classes in health…
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2017
Sentsova T.B., Tutelyan V.A., Chernyak O.O., Vorozhko I.V., Gapparova K.M.
Introduction. Currently questions on the role of genes polymorphism that regulate metabolism and implicated in metabolic disorders are disputed. Objective. The study of proteomic and metabolomic manifestations of different variants of apolipoprotein E genes po…
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2015
Nazarenko G.I., Zhuravlev Yu.I., Ryazanov V.V., Konstantinova M.V., Kleymenova E.B.
Introduction. Ischemic stroke (IS) is a multifactorial disease, resulting from a complex interaction of genetic and environmental factors. Individual cause of the disease, multiple factors and symptoms require advanced mathematical methods of predicting IS ris…