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Molecular Medicine Peer-reviewed scientific journal

Found: 4

ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2024 · pp. 38–44

DACARBAZINE INITIATES SIRT1-INDEPENDENT OVEREXPRESSION OF ANTI-APOPTOTIC BCL2 IN MELANOMA CELLS IN VIVO

Introduction. Cancer cell drug resistance in melanoma is associated with evasion of apoptosis-induced stimuli. Assessing the level of expression of the BCL2 and SIRT1 genes in distant organs and the tumor node makes it possible to assess the resistance of mela…

10.29296/24999490-2024-04-06Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2022 · pp. 50–55

INDUCTION OF APOPTOSIS OF PROSTATE CANCER CELLS BY THE EXTRACT OF THE FRESHWATER SPONGE

Introduction. Prostate cancer (PC) is by far the most commonly diagnosed malignant neoplasm of the urinary system. The pathogenesis and molecular mechanisms of prostate cancer remain incompletely understood. There are reports of the presence in the extracts of…

10.29296/24999490-2022-04-08Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2020

THE ROLE OF SWI/SNF CHROMATIN REMODELER COMPOSITION IN SENSITIVITY TO GSK126 AND ABT263

Introduction. Ovarian clear cell carcinoma (OCCC) is a subtype of epithelial ovarian cancer characterized by frequent mutations in the ARID1A gene and low sensitivity to standard-of-care chemotherapeutic agents. The aim of the study. To determine the role of A…

10.29296/24999490-2020-01-06Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2018

ABERRANT TRANSCRIPTIONAL ACTIVITY OF APOPTOSIS-REGULATING GENES IN MALIGNANT NEOPLASM OF CORPUS UTERI

Introduction. The most common invasive malignant tumor of uterine is endometrial cancer. In process of tissues malignancy the critical role belongs to changes in signaling pathways which regulate apoptosis. The aim of study was to analyze changes in the expres…

10.29296/24999490-2018-01-05Details ↗

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