Found: 6
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2022 · pp. 50–55
Nikolaev A.A., Gudinskaya N.I., Ushakova M.V.
Introduction. Prostate cancer (PC) is by far the most commonly diagnosed malignant neoplasm of the urinary system. The pathogenesis and molecular mechanisms of prostate cancer remain incompletely understood. There are reports of the presence in the extracts of…
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2020
Malygin A.S., Popov N.S., Demidova M.A., Shatokhina N.A.
Introduction. To assess the pharmacokinetic indices of new drugs, it is necessary to develop analytical methods for determining their concentration in biological objects. Purpose of the study. Development and validation of HPLC-mass spectrometric methods for t…
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2018
Lebedeva O.P., Zhukova I.O., Ivashova O.N., Pakhomov S.P., Churnosov M.I.
Introduction. Missed and spontaneous abortions are one of the most important causes of the reproductive loss. The aim of the study: to study specialties of mRNA expression of p53 and proteins of its signaling pathway in the decidual tissue at 6–10 weeks of ges…
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2018
Kit O.I., Vodolazhsky D.I., Kutilin D.S., Nikitin I.S., Moiseenko T.I., Frantsiyants E.M.
Introduction. The most common invasive malignant tumor of uterine is endometrial cancer. In process of tissues malignancy the critical role belongs to changes in signaling pathways which regulate apoptosis. The aim of study was to analyze changes in the expres…
Research article2014
Paltseva E.M., Semenova T.S., Zhigalova S.B., Pestin I.S., Shertsinger A.G.
Introduction. Despite the fact that portal hypertensive gastropathy (PHG) developing in patients with portal hypertension (PH) is a serious clinical problem, its pathogenesis remains to be poorly studied. The aim of our research was to study the proapoptotic p…
Research article2014
Yakushina V.D., Vasileva O.A., Ryazantseva N.V., Novitsky V.V., Starikova E.G., Tashireva L.A., Nebesnaya I.S.
Introduction. Galectin-1 binds to cell surface glycoprotein and participates in cooperation of immune cells. It is supposed that the CD4+- lymphocytes can be target for immunosuppressive activity of galectin-1. However, there is no sufficient information about…