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Molecular Medicine Peer-reviewed scientific journal

Found: 5

ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2022

Lungs and liver remodeling depends on the presence of metastasis in melanoma B16-bearing mice

Pre-metastatic niche formation precedes tumor dissemination although the mechanisms of it remain unclear. Therefore, the aim of the study was to evaluate the expression of molecules characterizing the microenvironment remodeling in target organs lungs and live…

10.29296/24999490-2022-01-07Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2017

ACTIVITY OF HIF PATHWAY IN EPIDERMIS AS CONTROL FACTOR FOR SKIN VASCULATURE

Introduction. The physiological state of the skin vasculature is largely determined by the influence of environmental factors, including the alteration of the oxygen partial pressure. Obviously, the epidermis, as the surface layer of the skin, should play a ke…

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ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2015

EXPERIMENTAL STUDY OF ANTITUMOR ACTIVITY OF NEW NITRIC OXIDE SYNTHASE INHIBITOR T1023

Introduction. Activation of eNOS/sGC/cGMP-pathway is a common link in the development of angiogenic action of the majority of pro-angiogenic factors. In this regard, the chemical inhibition of NOS (Nitric Oxide Synthase) may cause a nonspecific angiostatic eff…

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ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2015

A MORPHOFUNCTIONAL STUDY OF MESENCHYMAL STEM CELLS’ EFFECTS ON SARCOMA М-1

Introduction. The one of the most important problems of the modern regenerative medicine is incomplete understanding of the influence of mesenchymal stem cells (MSCs) on the growth of malignant neoplasms. Aim of the study. Analysis of the allogeneic MSCs’ effe…

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ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ

Lungs and liver remodeling depends on the presence of metastasis in melanoma B16-bearing mice

Pre-metastatic niche formation precedes tumor dissemination although the mechanisms of it remain unclear. Therefore, the aim of the study was to evaluate the expression of molecules characterizing the microenvironment remodeling in target organs lungs and live…

10.29296/24999490-2022-01-07Details ↗

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