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Molecular Medicine
Found: 7
Introduction. The study of the molecular mechanisms of skin aging is one of the key problems of dermatocosmetology. Inflamaging is a chronic low–level inflammation that occurs with age. This condition is characterized by a change in the expression of proteins …
Introduction. Tuberculosis is a socially significant disease, which is based on chronic granulomatous inflammation with the formation of fibrosis. The signaling molecules CD44 and ICAM-1 play an important role in the process of migration of immune cells from t…
Introduction. Under the influence of glioma cells, peritumoral zone astrocytes may acquire tumorigenic phenotype, particularly due to the suppression of immunocompetent cells. The aim of the study. Investigate the changes in the gene expression profile of glio…
The review considers the role of hyaluronic acid (HA), primarily low-molecular-weight fractions of HA, in the regulation of the cell cycle of tumor cells. The formation of a pool of low-molecular weight HA molecules is due to the high activity of hyaluronidase…
The review considers the system of hyaluronic acid (HA), represented by its receptors, the enzymes of synthesis (hyaluronan synthase), cleavage (hyaluronidase). The participation of the HA system in the regulation of the cell cycle was demonstrated. The most i…
Introduction. Cancer stem cells (CSCs), which are less sensitive to chemotherapeutic drugs than other tumor cells, play a key role in the initiation and development of the tumor process. Maintenance of CSCs determines the risk of cancer recurrence. The aim of …
Introduction. In spite of active research, no highly specific and sensitive marker of skin melanoma has been found so far. The aim of the study. Studying the level of stem cell factor (SCF), neuron-specific enolase (NSE), sCD44std, and heat shock proteins Hsp2…