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INVESTIGATIONS OF THE 125I-LABELLED TARGET MOLECULES DARPIN9_29 FOR RADIONUCLIDE DIAGNOSTICS OF MALIGNANT TUMORS WITH HER2/NEU OVEREXPRESSION

Bragina O.D., Vorobyeva A.G., Tolmachev V.M., Orlova A.M., Chernov V.I., Deev S.M., Proshkina G.N., Shulga A.A., Larkina M.S., Zelchan R.V., Sinilkin I.G., Medvedeva A.A.

Introduction. Her2/neu is one of the most studied molecular target the overexpression of which is associated with poor prognosis and aggressive course of the disease. The use of modern non-invasive radionuclide techniques with the application of highly affinit…