Search

EVALUATION OF N-GLYCOSYLATION PROFILE OF RECOMBINANT BLOOD COAGULATION FACTOR VIIa MOLECULE

Ustinnikova O.B., Rounova O.B., Movsesyants А.А., Shukurov R.R., Smolov M.A., Khamitov R.A.

Introduction. The specific activity of blood coagulation factor VIIa depends, among other things, on the presence of N-acetylneuraminic acid (sialic acid) and phosphate residues in the molecule. Thus the authenticity of glycosylation profile as one efficacy an…