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Molecular Medicine Peer-reviewed scientific journal

Found: 5

ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2023 · pp. 60–64

ANALYSIS OF THE RELATIONSHIP OF ITGB3, FV, AND FII GENE POLYMORPHISM WITH THE DEVELOPMENT OF DIABETIC FOOT SYNDROME

Introduction. There is a steady increase in the incidence of type 2 diabetes worldwide. One of the most formidable complications of this pathology is the development of diabetic foot syndrome, which is accompanied by up to 50% of cases of high amputations, dis…

10.29296/24999490-2023-04-08Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2020

EVALUATION OF N-GLYCOSYLATION PROFILE OF RECOMBINANT BLOOD COAGULATION FACTOR VIIa MOLECULE

Introduction. The specific activity of blood coagulation factor VIIa depends, among other things, on the presence of N-acetylneuraminic acid (sialic acid) and phosphate residues in the molecule. Thus the authenticity of glycosylation profile as one efficacy an…

10.29296/24999490-2020-04-08Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2020

STANDARDIZATION OF THE METHOD OF MULTI-TARGET SINGLE-NUCLEOTIDE ELONGATION FOR MOLECULAR GENETIC STUDY OF CYTOLOGICAL MATERIAL IN THYROID NEOPLASM

Introduction. Thyroid cancer (TC) is the most prevalent cancer among malignant neoplasms of the organs of the endocrine system. Cytological categories Bethesda III–V of TC are considered to be the most difficult for making a diagnosis. Molecular genetic tests …

10.29296/24999490-2020-06-05Details ↗
ОБЗОР2020

MOLECULAR MECHANISMS OF RESISTANCE DEVELOPMENT UNDER TARGETED THERAPY ON THE EXAMPLE OF CUTANEOUS MELANOMA

Cutaneous melanoma is a highly heterogeneous malignancy, which characterized by low effectiveness of chemotherapeutic antitumor agents. 50% of melanomas have a somatic mutation in BRAF oncogene, leading to uncontrolled activation of mitogen-activated protein k…

10.29296/24999490-2020-06-02Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2019

AGE FEATURES OF THE EXPRESSION OF SIGNAL MOLECULES – PROTEIN P53, COLLAGEN TYPE II, VEGF AND VEGFR IN BIOPTATES OF INTACT MYOMETRY IN UTERINE MYOMA

Introduction. Leiomyomas also called fibroids, is the most common benign gynecological tumor in premenopausal women. The complex pathogenesis shows multiple biogenetical and multifactorial aspects to influence the etiology and growth of leiomyomas. A clinical …

10.29296/24999490-2019-06-11Details ↗

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