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Molecular Medicine Peer-reviewed scientific journal

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ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2023 · pp. 33–38

Activation of the MAPK signal cascade components phosphorylation involved in the formation of the G0-positive tumor phenotype

Introduction. Among the heterogeneous population of tumor cells, there are so-called dormant and senescent cells located in the G0 phase of the cell cycle. The transition to the G0 phase is a stress response mediated, for example, by treatment with chemotherap…

10.29296/24999490-2023-02-05Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2022 · pp. 39–43

CYCLINE DEPENDENT KINASE 4 DECREASED LEVEL IN THE POPULATION OF Ki-67-NEGATIVE MELANOMA CELLS

Introduction. A transition of proliferating cancer cells to a G0 phase of a cell cycle considered to be implicated in cancer cell drug resistance. The aim of the study. A separation of G0-positive melanoma B16 cells fraction that correspond to resting followed…

10.29296/24999490-2022-06-06Details ↗

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