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Molecular Medicine Peer-reviewed scientific journal

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ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2026 · pp. 9–14

Age-related changes in 5xFAD microglia

Introduction. Microglia initiate and play a key role in neuroinflammation, which is currently considered one of the main mechanisms of neurodegeneration in Alzheimer’s disease. The aim of this study was to analyze the morphofunctional characteristics of microg…

10.29296/24999490-2026-03-02Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2025 · pp. 14–20

Levels of GFAP, Iba1, TNF-α, and caspase-3 in the cingulate cerebral cortex of mice after intraperitoneal lipopolysaccharide

Introduction. Bacterial lipopolysaccharide (LPS) affects the structure and function of nervous tissue cells. The aim of the study: to explore the impact of intraperitoneal LPS given to mice on levels of such markers as glial fibrillar acidic protein (GFAP), ad…

10.29296/24999490-2025-06-03Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2021

EXPRESSION OF GLIAL MARKERS, CYTOKINES AND MARKERS OF NEUROGENESIS IN THE MOUSE HIPPOCAMPUS DURING AGING AND IN RESPONSE TO LIPOPOLYSACCHARIDE

Introduction. Aging is associated with a decrease in the neuro- and synaptogenesis as well as hyperactivation of glial cells, which leads to changes in the morphofunctional state of the nervous tissue of the hippocampus and, as a consequence, a deterioration i…

10.29296/24999490-2021-03-06Details ↗

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