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Interferon signature as a tool for stratifying response to immunomodulatory complexes of yeast RNA and ascorbic acid: molecular markers and prospects for personalized application

Potupchik T.V., Ermolaev V.V., Generalov S.V., Alikin Yu.S., Evert L.S., Fedotova T.S., Grishina K.N., Vladimirova D.S.

Introduction. Immunomodulatory complexes based on yeast RNA and ascorbic acid are regarded as a natural multitarget platform capable of affecting innate immune receptors, interferon signaling and cellular redox balance. However, variability of the interferon r…