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Molecular Medicine Peer-reviewed scientific journal

Found: 3

ОБЗОР2026 · pp. 84–94

Digital twin of early immunometabolic response after tick bite. LC-MS/MS profiling of lipid mediators and the kynurenine pathway in a QSP model of systemic inflammation

Tick bite is traditionally viewed in clinical practice primarily as an event associated with the risk of pathogen transmission. Although this interpretation is epidemiologically justified, it does not capture the molecular layer that develops within the first …

10.29296/24999490-2026-02-11Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2026 · pp. 31–38

Proteomic reprogramming of senescent mesenchymal stromal cells of adipose tissue: a role in the modulation of macrophage phenotype and the formation of inflammageing in obesity

The study is devoted to the identification of changes in the proteomic profile of senescent mesenchymal stromal cells of adipose tissue, which determine the modulation of the macrophage phenotype and are involved in the pathogenetic cascade of the formation of…

10.29296/24999490-2026-02-04Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2020

DEVELOPMENT AND VALIDATION OF HPLC-MS/MS METHOD OF DETERMINATION OF A NEW VALPROIC ACID DERIVATIVE AND 1,3,4-THIADIAZOLE IN RAT BRAIN

Introduction. To assess the pharmacokinetic indices of new drugs, it is necessary to develop analytical methods for determining their concentration in biological objects. Purpose of the study. Development and validation of HPLC-mass spectrometric methods for t…

10.29296/24999490-2020-04-06Details ↗

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