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CLINICAL AND GENETIC CHARACTERISTICS OF RUSSIAN PATIENTS WITH LYNCH SYNDROME

Tsukanov A.S., Pospekhova N.I., Shubin V.P., Sachkov I.Yu., Achkasov S.I., Rybakov E.G., Frolov S.A., Kashnikov V.N., Shelygin Yu.A.

Aim. Lynch Syndrome, which is caused by a defect in one of the mismatch repair (MMR) genes, is the most common among all hereditary colorectal cancer syndromes. Patients with Lynch syndrome in different populations are inherent in both genetic and clinical fea…