This website is intended for professionals in medicine and healthcare. By selecting “Confirm”, I declare that I am a member of this professional audience. I also agree to the publisher’s rules for using its information resource. Publisher’s resource rules (Russian)
Molecular Medicine
Found: 8
Introduction. This review is devoted to the problem of the pathogenesis of pain syndrome in multiple myeloma (MM). The severity of pain often correlates poorly with the plasma cell burden but is highly dependent on tumor aggressiveness determined by primary ge…
Introduction. Prolapse of pelvic organs being extremely common in the female population, hence, it is important to search for factors of prolapse pathogenesis to identify markers of the optimal time for surgical intervention. The aim of the study is to investi…
Introduction. The search of molecular markers for early diagnostics, prognosis, and identification of new objects for molecular-targeted therapy of primary bone tumors remains one of the most important tasks despite the significant achievements in the treatmen…
Introduction. Search for correct markers for diagnosis, prognosis and evaluation of the effectiveness of chemotherapy is the most important problem of the modern oncohematology. The aim. To determine the clinical relevance of matrix metalloproteinase-2 (MMP-2)…
Introduction. The paper presents basic information about the modern role of the IMF in various biochemical processes. Emphasis is placed on the role of MMPs in the pathogenesis of periodontitis. These published data suggest ambiguity of scientific views on the…
Introduction. Matrix metalloproteinase (MMP) – a family of extracellular zinc-containing proteases. There are currently 25 known MMP. Increased activity of MMP observed in some physiological processes – during the follicular phase of the menstrual cycle and du…
The immunohistochemical expression of MMP-2 and MMP-3 in carcinomas of the stomach, differed by product MUC1, 2, 5AС, 6 and CD10 has been investigated. In mixed carcinomas immunophenotypic variant parameters of studied MMP expression were significantly higher …
Publications devoted to the role of various representatives of matrix metalloproteinases (MMPs) family and their tissue inhibitors in ovarian cancer in differential diagnostics, prognosis and in the development of new treatment modalities are critically analyz…