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Molecular Medicine Peer-reviewed scientific journal

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ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2026 · pp. 31–38

Proteomic reprogramming of senescent mesenchymal stromal cells of adipose tissue: a role in the modulation of macrophage phenotype and the formation of inflammageing in obesity

The study is devoted to the identification of changes in the proteomic profile of senescent mesenchymal stromal cells of adipose tissue, which determine the modulation of the macrophage phenotype and are involved in the pathogenetic cascade of the formation of…

10.29296/24999490-2026-02-04Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2023 · pp. 33–38

Activation of the MAPK signal cascade components phosphorylation involved in the formation of the G0-positive tumor phenotype

Introduction. Among the heterogeneous population of tumor cells, there are so-called dormant and senescent cells located in the G0 phase of the cell cycle. The transition to the G0 phase is a stress response mediated, for example, by treatment with chemotherap…

10.29296/24999490-2023-02-05Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2019

STUDY OF EXPRESSION OF MMP-1 GENE IN LOCALIZED SСLERODERMIA

The aim of the study was to investigate the expression of the MMP-1 gene in patients with a diagnosis of localized scleroderma. Methods. The study included 12 patients with an established diagnosis of localized scleroderma. The material of the study consisted …

10.29296/24999490-2019-02-04Details ↗

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