Found: 5
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2026 · pp. 3–8
Khaspekov L.G., Mudarisova R.S., Kolotyeva N.A., Salmina A.B., Li W., Illarioshkin S.N.
Introduction. Parkinson’s disease (PD) is a chronic, progressive neurodegenerative disorder, the primary pathological feature of which is the death of dopaminergic neurons in the substantia nigra pars compacta and the accumulation of aggregated α-synuclein. Th…
ОБЗОР2025 · pp. 16–26
Tereshchenko S.Yu., Potupchik T.V., Evert L.S., Alieva L.G., Kozyrina Y.E., Maremkulov A.A.
Objective. To analyze the current state of preclinical and clinical studies in genome editing for neurodegenerative diseases, evaluate its potential impact on clinical practice, and examine ethical aspects of these technologies’ application. Material and metho…
ОБЗОР2024 · pp. 16–22
Mikashinovich Z.I., Telesmanich N.R., Smirnova O.B., Chernogubova E.A.
Introduction. Despite numerous studies in the field of neurodegenerative diseases, the exact mechanisms of these processes have not yet been identified. The purpose of this review is to analyze the methodological approaches necessary to revise the traditional …
ОБЗОР2020
Kozhevnikova E.O., Melnikova E.V., Rachinskaya O.A., Semenova I.S., Merkulov V.A.
Progress in clinical research and medicine has contributed to a significant reduction in the worldwide mortality rate. Currently, the strategy of developed countries is directed at increasing expectancy and improving life quality. As a consequence, the modern …
ПЕРЕДОВАЯ СТАТЬЯ2018
Paltsev M.A., Zuev V.A., Diatlova A.S., Linkova N.S., Kvetnaia T.V.
Parkinson’s disease (PD) is a progressive, age-related, neuronal disorder that affects as much as 1% of the persons over 65 years. According to forecasts of the World Health Organization over the world about 9 million people will suffer from PD by 2030. So PD …