Found: 5
ОБЗОР2026 · pp. 100–106
Potupchik T.V., Ermolaev V.V., Generalov S.V., Alikin Yu.S., Evert L.S., Kurbanova D.V., Shevchuk A.S., Omarova L.S.
Introduction. Single-stranded yeast RNA–ascorbic acid complexes are of interest as a class of natural immunomodulatory systems combining activation of innate immune pattern-recognition receptors with redox-modulating and epigenetic effects of vitamin C. Russia…
ОБЗОР2026 · pp. 65–74
Potupchik T.V., Alikin Yu.S., Generalov S.V., Ermolaev V.V., Kudlay D.A., Ksanaeva J.A., Banar L.S., Makhova A.A.
Introduction. Yeast RNA is considered a promising class of natural immunomodulators that has been studied in Russian biomedical science since the Soviet period. High-molecular-weight RNA fractions from Saccharomyces cerevisiae exhibit pronounced immunostimulat…
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2026 · pp. 31–38
Potupchik T.V., Alikin Yu.S., Generalov S.V., Ermolaev V.V., Pluzhnikova A.V., Ferzilaeva N.R., Kozarenko M.A.
Introduction. Innate immunity represents the first line of defense against pathogens, based on recognition of conserved molecular patterns (PAMPs) through specialized pattern recognition receptors (PRRs). RNA-containing viral patterns are of particular importa…
ОБЗОР2025 · pp. 76–83
Potupchik T.V., Alikin Yu.S., Generalov S.V., Evert L.S., Tymchuk V.I., Khalakoeva D.A., Abdullaeva S.R., Spitsyn А.А
Introduction. Ascorbic acid (vitamin C) is an essential cofactor of numerous enzymatic reactions and possesses pronounced antioxidant properties. Recent years have seen accumulating evidence of its immunomodulatory effects, particularly the ability to potentia…
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2016
Zherebiatiev A.S., Kamyshny A.M., Kamyshnaya V.A.
Introduction. The pathogenesis of inflammatory bowel disease is complex and multifactorial. Studies have led to the current concept that the T-helper cells are components of the adaptive immune response whereas Toll-like receptors, NOD-like-receptors, RIG-I-li…