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EPIGENETIC CHANGES IN COLORECTAL CANCER: THE ROLE OF SEPT9 METHYLATION IN THE DIAGNOSIS AND PROGNOSIS OF THE DISEASE COURSE

Toropova A.V., Nazarov V.D., Lapin S.V., Zakharenko A.A., Ten O.A., Filatova I.A., Fedorova P.A., Devyatkin E.A., Musonova M.K., Slivinskiy D.S., Nikitina V.A.

Introduction. Colorectal cancer (CRC) remains one of the leading oncological diseases, the development of which is accompanied by characteristic epigenetic changes. The most significant of these is the hypermethylation of the SEPT9 gene, detected both in tumor…