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Molecular Medicine Peer-reviewed scientific journal

Found: 3

ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2017

INFLUENCE OF SLCO1B1 GENE C.T521>C POLYMORPHISM ON THERAPY WITH SIMVASTATIN IN CORONARY HEART DISEASE PATIENTS

Introduction. Carrier protein OATP1B1, encoded by the SLCO1B1gene, is involved in the transport of simvastatin into liver cells. SLCO1B1 gene polymorphisms influence on the functionality of the transporter, which could reflect on the efficacy and safety of tre…

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ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2016

GENE SLCO1B1 ASSOCIATED WITH STATIN-INDUCED MYOPATHY IN RUSSIAN AND SAKHA (YAKUTIA) STATIN INTAKE PATIENTS SUFFERED FROM HYPERLIPIDEMIA

Introduction. SLCO1B1 encodes the organic anion-transporting polypeptide which has been shown to regulate the hepatic uptake of statins. SLCO1B1*5 genetic variant is associated with the high risk for statin-induced myopathy in patients with statins therapy. Ai…

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