Research article2014
TYMS GENE POLYMORPHISMS IN PATIENTS WITH GASTRIC CANCER, THE RELATIONSHIP WITH LONG-TERM RESULTS OF COMBINED TREATMENT
Introduction. Thymidylate synthase (TS) is a key enzyme in nucleotide biosynthesis and is the main intracellular target of 5-FU. We investigated the clinical and prognostic importance of TYMS gene 5' (TSR2/TSR3 and G>C) and 3' (del 6) untranslated region polym…