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THE ROLE OF BRAIN-DERIVED NEUROTROPHIC FACTOR IN THE PATHOGENESIS OF DEPRESSIVE DISORDERS

Shepeleva I.I., Chekhonin I.V., Chernysheva A.A., Kardashova K.Sh., Voznyakovskaya E.V., Gurina O.I.

The neurotrophic hypothesis of depressive disorders has gained widespread recognition nowadays. This review is devoted to the brain-derived neurotrophic factor (BDNF) system in the pathogenesis of depression and major depressive disorder. We describe the struc…