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Molecular Medicine
Found: 3
Introduction. Sirtuins (SIRTs) are NAD+-dependent histone deacetylases involved in the intracellular regulation of multiple biological processes including DNA repair, autophagy, inflammation, oxidative stress defence and metabolism associated with age-associat…
The senescence-associated secretory phenotype (SASP) is one of the causes of age-associated diseases, including atherosclerosis. The purpose of the review is to analyze data on the role of SASP cells of the cardiovascular system in the pathogenesis and pharmac…
The purpose of the review was the search and analysis of the data about hormone adropin, similar to the known hormone irisin, and its effect on the pathology, associated with aging. Adropin is expressed in many following organs as referred to CNS, in liver, ki…