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Molecular Medicine
Found: 3
Introduction. Alternative splicing of telomerase catalytic subunit hTERT (human Telomerase Reverse Transcriptase) regulates the telomerase activity. The increased expression of non-active spliced hTERT results in inhibition of telomerase. However, very little …
Telomerase catalytic subunit hTERT is tightly regulated both at the transcriptional and posttranscriptional levels. One of the regulatory mechanisms is its mRNA alternative splicing. Only full-length form has catalytic activity and the ability to elongate telo…
IL15 proves to be a cytokine that important for innate as well as for adaptive immunity. It is one of the key factors of cell-mediated antiviral response. In this review we touch upon its primary, secondary and tertiary structure and functions, characteristics…