ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2026 · pp. 34–43
Zhuravleva A.N., Naumov A.V.
Introduction. Primary open-angle glaucoma is considered a multifactorial disease, in the pathogenesis of which low-grade inflammation, cytokine imbalance, extracellular matrix remodeling, and neuroinflammation play a significant role. In comorbid patients with…
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2022 · pp. 45–52
Barinov E.F., Malinin Y.Yu., Grigoryan Kh.V.
The reasons for the low efficiency of the α1A-blockers using in the scheme of lithokinetic therapy (LCT) remain unclear. The aim of the study was to evaluate the activity of the purinergic P2X1 receptor in the blockade of the α1A-adrenergic receptor during LCT…
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2018
Topchieva L.V., Balan O.V., Malysheva I.E., Barysheva O.Yu., Marusenko I.M., Vaskova O.A.
The aim of this work was to study the effect of methotrexate, glucocorticoids and nonsteroidal anti-inflammatory drugs on the plasma levels of nitric oxide metabolites, as well as the level of NOS2 gene transcripts in peripheral blood leukocytes (PBL) in rheum…