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Molecular Medicine
Found: 6
Relevance: The review is devoted to the analyses of literature data on disorders of the immune system in COVID-19. Since some of the clinical symptoms of COVID-19 are consistent with those of autoimmune diseases, one of the fundamental questions about COVID-19…
Little is known about the etiology of neuropsychiatric disorders. Glutamate-mediated excitotoxicity is one of the main pathological mechanisms occurring in various types of acute and chronic diseases of the central nervous system. Glutamate is the major excita…
Anti-glutamate decarboxylase (GAD65 isoform) autoantibodies are present in the blood of patients with such various autoimmune disorders, as diabetes type I, as well as relatively rare neurological diseases, such as Stiff Person syndrome and cerebellar ataxia. …
Introduction. The quantitative determination and isotyping of autoantibodies to a clinically significant protein – glutathione-S-transferase (GST) in blood serum samples is relevant for monitoring and predicting the dynamics of autoimmune processes. The aim of…
Introduction. The laboratory diagnosis of celiac disease is based on the detection of antibodies against deamidated gliadin peptides (anti-DGP), autoantibodies to tissue transglutaminase (anti-tTG) and endomysium (AEA), as well as genotyping of HLA-DQ2/8 loci.…
Introduction. A lot of factors of innate and specific immunity are involved in development of the autoimmune diseases – multiple sclerosis (MS) that cause the damages of myelin envelopes of nerve fibres with irreversible neurological consequences. To decrease …