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MOLECULAR AND CELLULAR TARGETS AS THE BASISOF PRECLINICAL DIAGNOSIS OF TYPE 1 DIABETES: PROBLEMS AND PROSPECTS

Gnatenko D.A., Kostyushev D.S., Andreeva A.V., Filatova G.A., Notkins A., M. von Herrath, Paltsev M.A., Suchkov S.V.

In autoimmune diabetes mellitus (IDDM), clinical manifestation is typically preceded by several years of latent autoimmune insulitis. The autoimmune process arises only in genetically predisposed people,and is usually provoked by an infectious pathogen. Dagnos…