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Molecular Medicine Peer-reviewed scientific journal

Found: 7

ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2025 · pp. 21–30

Immunohistochemical study of somatostatin and dopamine receptors (SSTR2, SSTR5, DR2) in pituitary adenomas to justify targeted therapy

Introduction. Adenomas are the most common disease affecting the pituitary gland. Most of these tumors can be successfully treated. The main method is transsphenoidal resection. The exception is prolactinomas, which are treated with dopamine agonists. Objectiv…

10.29296/24999490-2025-05-03Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2019

THE STUDY OF THE ACUTE TOXICITY OF NEW RADIOPHARMACEUTICALS 99mTc-1-thio-D-glucose IN THE EXPERIMENT

The aim of the study. To investigate the overall acute toxicity of a new radiopharmaceutical in laboratory animals under the selected experimental conditions. Materials and methods. The study was performed on 80 white outbred rats (weight of males 220–260 g, t…

10.29296/24999490-2019-01-09Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2019

CORRELATION BETWEEN CARDIAC TROPONIN I LEVELS AND AREA OF MYOCARDIAL VASCULAR NECROSIS IN THE PATIENTS WITH FATAL OUTCOME

Introduction. The scale of myocardial infarction plays a key role in the prognosis of the disease. Changes in contractile activity of myocardial tissue as a result of necrosis of cardiomyocytes is the decisive factor in this issue. The aim of the study. The pu…

10.29296/24999490-2019-05-04Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2017

PLURIHORMONAL CELLS OF ANTERIOR PITUITARY. NEW FEATURES TO OPTIMIZE MOLECULAR DIAGNOSIS OF NEUROENDOCRINE TUMORS

Introduction. Multihormonality is an ability of pituitary cells to produce more than one hormone. A great number of adenomas are multihormonal in the actual practice. We hypothesize cells of a normal pituitary gland to secret several hormones simultaneously. O…

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ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2017

CHARCTERISTICS OF CHANGES OF COLLGEN MAIN TYPES I–VI IN CALCIFIC AORTIC VALVE STENOSIS PATHOGENESIS

Introduction. The gain of elderly persons in the population of industrial countries provides a high actuality to investigations of pathogenesis of calcific aortic valve stenosis (CAVS). The aim of the study. To specify the quality and quantity pattern of colla…

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ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2015

GE-ASSOSIATED ASPECTS OF THE EXPRESSION OF HUMAN ENDOTHELIAL SIGNAING MOLECULES AND THEIR ROLE IN THE DEVELOPMENT OF CARDIO-VASCULAR PATHOLOGY

Introduction. Age-assosiated endothelial changes are one of the reasons of the development of cardio-vascular pathology. Moreover, molecular mechanisms of human endothelium aging are investigated only slightly. Thus, the problem of pathogenesis of cardio-vascu…

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ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2015

EXPRESSION OF AORTA ENDOTHELIUM SIGNALING MOLECULES IN AGEING AND ATHEROSCLEROSIS

Introduction. Atherosclerosis proves to be age-dependent and social significant pathology. Knowledge of the role of signaling molecules in its development, and the elaboration on this basis molecular markers of restenosis after stenting of arteries remains to …

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