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ОБЗОР2025 · pp. 19–29

Molecular mechanisms and pharmacogenetic determinants of II–III generation antihistamines efficacy in allergic bronchial asthma: personalized therapy prospects

Borodulina E.A., Yakovleva E.V., Borodulin B.E., Gladunova E.P., Marchenko S.D., Krylova O.V., Mamontova E.R., Rekalo A.R., Minnullina Z.R., Bagirova B.R., Salpagarova A.A.

Introduction. Allergic bronchial asthma (BA) is accompanied by activation of histamine H1/H4 receptors and variable response to antihistamines. The aim of this review is to analyze the molecular mechanisms of action of second- and third-generation antihistamin…

10.29296/24999490-2025-03-03Details ↗

Research article2014

PROSPECTS OF TETRAPEPTIDE APPLICATION IN TREATMENT OF CHRONIC BRONCHITIS: MOLECULAR MECHANISMS

Khavinson V.Kh., Ryzhak G.A., Lin'kova N.S., Ashapkin V.V., Drobintseva A.O., Basharina V.S., Vanyushin B.F.

Introduction. Chronic bronchitis is one of the socially significant diseases. Accordingly, a search of the new more effective and safe bronchoprotective drugs is the one of aims of molecular medicine. The aim of the study. The goal of our research was the inve…

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