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Molecular Medicine
Found: 12
Introduction. Bacterial lipopolysaccharide (LPS) affects the structure and function of nervous tissue cells. The aim of the study: to explore the impact of intraperitoneal LPS given to mice on levels of such markers as glial fibrillar acidic protein (GFAP), ad…
Relevance. The review is devoted to the analysis of modern ideas about the functional role of connexins in intercellular interactions, their participation in maintaining cellular and tissue homeostasis and in the pathogenesis of diseases of the respiratory sys…
Introduction. Urological and genital malignant neoplasms in men are an urgent problem. Every year, about 403.3 thousand newly diagnosed cases of kidney cancer and 34.5 thousand of penile cancer are registered in the world. With metabolic atypism, a change in a…
Lung cancer occupies the leading position in at the structure of oncological morbidity in the developed countries. The overall five-year survival rate for lung cancer isn’t exceed to 10–20% even using of the entire modern arsenal of therapeutic methods. Multip…
Introduction. The risk of bone tissue disturbance leading to a disability of diabetes mellitus patients brisks up the study of the mechanisms of diabetic osteopathy. The aim of the study. To study the indices of collagen exchange, the content of components of …
Introduction. Vitamin D is one of the main regulators of phosphorus-calcium metabolism. Vitamin D availability is determined by both external and genetic factors. The genetic contribution to the 25 (OH) D level is estimated to range from 23 to 77%. According t…
Purpose. To study pharmacokinetic parameters in studies of a comparative bioavailability in combination with the assessment of homeostatic mechanisms of the regulation on the example of calcium. Methods. There were studied pharmacokinetic parameters of calcium…
Introduction. The gain of elderly persons in the population of industrial countries provides a high actuality to investigations of pathogenesis of calcific aortic valve stenosis (CAVS). The aim of the study. To specify the quality and quantity pattern of colla…
Calbindin 28 kDa, calretinin and parvalbumin are referred to calcium-binding proteins which are both widely distributed in the nervous system and selectively expressed in certain population of neurons. These proteins are expressed not only in the central nervo…
Alzheimer's disease being the socially significant neurodegenerative disease of the elderly, ranks 6th on the causes of death among somatic pathologies. The molecular mechanisms of Alzheimer's disease still remain unexplored until the end, and the efficacy of …
Introduction. Mediator release from mast cells or basophils is the key event in many acute allergic and inflammatory processes. Rat basophilic leukemia cell line RBL-2H3 cells is widely used as a model for studying mast cells degranulation. Aim of the study. T…
In a series of laboratory experiments on the surface of dentin treated with etching gel – 38% Phosphoric Acid, and exposed to 95% ethanol solution for 30 days at ambient temperature the crystal structures have been found. Three-Dimensional Visualization of the…