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Molecular Medicine Peer-reviewed scientific journal

Found: 7

ОБЗОР2024 · pp. 13–20

INTERLEUKIN-11 AND CARDIOVASCULAR PATHOLOGY

Cardiovascular disease (CVD) is a leading cause of morbidity and mortality. An important task in cardiology is the search and study of new biomarkers. Scientific interest is actively focused on the study of interleukin-11 (IL-11). The purpose of the literature…

10.29296/24999490-2024-01-02Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2021

SALIVA CONCENTRATION OF SIRTUINS: PERSPECTIVES OF APPLICATION FOR CORONARY HEART DISEASE DIAGNOSTICS AND AGING RATE

The aim is the comparative analysis of saliva concentration of sirtuins, in middle age and elderly people without cardiovascular pathology (CP) and with coronary heart disease (CHD). Methods. Saliva was obtained from healthy donors (73 persons without CP, «nor…

10.29296/24999490-2021-06-06Details ↗
ОБЗОР2021

Osteopontin as a factor of neuroinflammation in chronic non-infectious diseases

Osteopontin (OPN) is a highly phosphorylated multifunctional glycosphoprotein with important functional activity in cancer and cardiovascular diseases, diabetes mellitus (DM), kidney and liver pathology, inflammatory process, and also influencing cell viabilit…

10.29296/24999490-2021-03-04Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2019

ICAM-1, IL-6, TROPONIN-1 IN THE BUCCAL EPITHELIUM AS PREDICTORS OF THE ATHEROSCLEROSIS DEVELOPMENT IN PERSONS OF DIFFERENT AGES

The task of molecular vital diagnosis is to search for peripheral tissues for the verification of biomarkers with the aim of optimization of diagnosis and evaluation of the effectiveness of treatment of socially significant diseases including cardiovascular pa…

10.29296/24999490-2019-01-06Details ↗
ОБЗОР2019

OMICS TECHNOLOGY: THE ROLE AND SIGNIFICANCE FOR PERSONALIZED MEDICINE

Personalized medicine implements new methods of molecular diagnostic for increasing the efficacy of the treatment of patients and the verification of the liability to diseases. Thus the search, development and applying modern methods and technologies of biomed…

10.29296/24999490-2019-04-01Details ↗
ОБЗОР2018

SALIVA AS A BIOLOGICAL OBJECT FOR NON-INVASIVE MOLECULAR DIAGNOSIS OF CARDIOVASCULAR DISEASES

Cardiovascular diseases (CVD) are considered to be one of the leading causes of lethality in patients of older age groups. In the last decade, the issue of finding a material for effective non-invasive diagnosis of CVD has become urgent. The review considers t…

10.29296/24999490-2018-05-01Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2017

ASSOCIATION OF INFECTIVE ENDOCARDITIS WITH GENE POLYMORPHISMS OF THE PHASE II XENOBIOTIC DETOXICATION SYSTEM ENZYMES

Introduction. Pathogenesis of infective endocarditis (IE) is not quite clear till now. In last years research of variants of the genes connected with pathogenesis of IE was performed. The aim. The investigation of IE association with gene single-nucleotide pol…

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