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MOLECULAR PATHOGENESIS AND MARKERS FOR RENAL CELL CARCINOMA

Shirshova A.N., Boyarskikh U.A., Filipenko M.L., Pokrovsky V.S., Kushlinskii N.E.

The review highlights current data on molecular pathogenesis and potential markers of clear cell renal cell carcinoma, obtained in MultiOmyx studies. Key molecular mechanisms of the pathogenesis of RCC are the loss of functions of the VHL, PBRM1, SETD2, BAP1, …