ОБЗОР2026 · pp. 107–116
Genetic architecture and molecular mechanisms of cerebrovascular diseases: ischemic stroke, cerebral small vessel disease and intracranial aneurysms in the context of personalized medicine
Introduction. Cerebrovascular diseases are a heterogeneous group of conditions shaped by the interaction of polygenic susceptibility, rare monogenic variants, vascular remodeling, neuroinflammation, dysregulated hemostasis, and epigenetic reprogramming. Recent…