ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2023 · pp. 40–48
Gilyazova I.R., Asadullina D.D., Ivanova E.A., Izmailov A.A., Kudlay D.A., Gilyazova G.R., Galimova E.F., Ermakov I.B., Rakhimov R.R., Popova E.V., Nasretdinov A.F., Sultanbaev A.B., Khusnutdinova E.K., Pavlov V.N.
Despite significant advance in clear cell renal cell carcinoma treatment, immune checkpoint inhibitors (ICIs) still have limited therapeutic efficacy. Taking into account the resistance to immunotherapy, observed in malignant neoplasms, the search for predicti…
ОБЗОР2019
Shirshova A.N., Boyarskikh U.A., Filipenko M.L., Pokrovsky V.S., Kushlinskii N.E.
The review highlights current data on molecular pathogenesis and potential markers of clear cell renal cell carcinoma, obtained in MultiOmyx studies. Key molecular mechanisms of the pathogenesis of RCC are the loss of functions of the VHL, PBRM1, SETD2, BAP1, …