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Molecular Medicine Peer-reviewed scientific journal

Found: 7

ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2025 · pp. 79–88

Glutathione: a key molecule of redox homeostasis and its potential for nutritional and metabolic regulation. a review of the literature

Introduction. Glutathione (GSH) is a key intracellular antioxidant involved in maintaining redox homeostasis, detoxifying xenobiotics, regulating immune and neurotransmitter systems, and supporting protein folding and degradation. Depletion of GSH is associate…

10.29296/24999490-2025-05-09Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2025 · pp. 34–40

Efficacy of antitumor therapy schemes with carboplatin in an experimental model of lung carcinoma and drug-resistant tuberculosis

Introduction. Up to 20% of tuberculosis patients suffer from malignant neoplasms. In this case, the combination of both diseases in the lung is a particular problem. More than 60% of patients cannot complete combination therapy due to drug-resistant MBT. The a…

10.29296/24999490-2025-01-04Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2024 · pp. 21–28

BIOLOGICAL MODEL OF LUNG CANCER COMBINATION AND TUBERCULOSIS: DEVELOPMENT FOR PRECLINICAL STUDY OF RATIONAL COMBINATIONS OF TARGETED ANTITUMOR AND ANTITUBERCULOSIS THERAPY

Introduction. Lung cancer occupies a leading position in the structure of mortality from cancer. Chronic inflammation characteristic of tuberculosis increases the risk of lung cancer. Currently, more and more information is emerging confirming the cause-and-ef…

10.29296/24999490-2024-02-04Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2021

PHASE I CLINICAL STUDY OF A NEW RADIOPHARMACEUTICAL BASED ON RECOMBINANT TARGET MOLECULES DARPIN9_29 LABELED WITH 99mTECHNETIUM FOR RADIONUCLIDE DIAGNOSIS OF THE Her2/neu-POSITIVE BREAST CANCER

Introduction. The main attention of researchers is paid to the study of one of the members of the EGF family – the receptor of epidermal growth factor 2 (Her2/neu), the overexpression of which is detected in 15–20% of cases of invasive breast cancer and had an…

10.29296/24999490-2021-02-06Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2015

THE EFFICACY AND SAFETY OF DIINDOLYLMETHANE IN THE VAGINAL SUPPOSITORY DOSAGE FORM IN THE TREATMENT OF CERVICAL INTRAEPITHELIAL NEOPLASIA

The aim of the study. The clinical study of the efficacy and safety of the novel pharmaceutical composition Cervicon-DIM on the base of diindolylmethane (DIM) in vaginal suppository form in the course of the conservative treatment of cervical intraepithelial n…

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Research article2013

THE STUDY OF TOXIC AND ALLERGENIC PROPERTIES OF THE NEW PHARMACEUTICAL COMPOSITIONOF DIINDOLYLMETHANE

Preclinical experimental study of toxic and allergenic properties of new pharmaceutical composition of diindolylmethane was carried on in various doses. It was established that tested drug refers to toxicity class V (almost non-toxic pharmaceutical substance) …

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