Found: 7
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2025 · pp. 79–88
Shrayner E.V., Bystrova V.I., Pokushalov E.A., Romanova A.D., Markin D.S., Kudlay D.A.
Introduction. Glutathione (GSH) is a key intracellular antioxidant involved in maintaining redox homeostasis, detoxifying xenobiotics, regulating immune and neurotransmitter systems, and supporting protein folding and degradation. Depletion of GSH is associate…
ОБЗОР2025 · pp. 3–11
Kokhanov A.V., Bisalieva R.A., Ebzeeva L.Kh.
Introduction. This review is devoted to the study of the structure, properties, evolution of hemoglobins, biochemical and clinical aspects of the use of neuroglobin (Ngb) and fetal hemoglobin (HbF) in health and in ischemic hypoxia of the brain. Material and m…
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2025 · pp. 34–40
Kudriashov G.G., Krylova Yu.S., Zmitrichenko Yu.G., Tochilnikov G.V., Afafonov G.M., Vinogradova T.I., Yablonskii P.K.
Introduction. Up to 20% of tuberculosis patients suffer from malignant neoplasms. In this case, the combination of both diseases in the lung is a particular problem. More than 60% of patients cannot complete combination therapy due to drug-resistant MBT. The a…
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2024 · pp. 21–28
Krylova Yu.S., Kudriashov G.G., Tochilnikov G.V., Vinogradova T.I., Dokhov M.A., Yablonskii P.K.
Introduction. Lung cancer occupies a leading position in the structure of mortality from cancer. Chronic inflammation characteristic of tuberculosis increases the risk of lung cancer. Currently, more and more information is emerging confirming the cause-and-ef…
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2021
Bragina O.D., Chernov V.I., Larkina M.S., Stasyuk E.S., Zelchan R.V., Medvedeva A.A., Garbukov E.Yu., Vernadskyi R.Yu., Deev S.M., Tolmachev V.M.
Introduction. The main attention of researchers is paid to the study of one of the members of the EGF family – the receptor of epidermal growth factor 2 (Her2/neu), the overexpression of which is detected in 15–20% of cases of invasive breast cancer and had an…
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2015
Ashrafian L.A., Sukhikh G.T., Kiselev V.I., Apolikhina I.A., Paltsev M.A., Drukh V.M., Kuznetsov I.N., Muyzhnek E.L.
The aim of the study. The clinical study of the efficacy and safety of the novel pharmaceutical composition Cervicon-DIM on the base of diindolylmethane (DIM) in vaginal suppository form in the course of the conservative treatment of cervical intraepithelial n…
Research article2013
Druh V.M., Paltcev M.A., Kiselev V.I., Kuznetsov I.N., Ashrafyan L.A., Muyjnek E.I., Pchelintseva O.I.
Preclinical experimental study of toxic and allergenic properties of new pharmaceutical composition of diindolylmethane was carried on in various doses. It was established that tested drug refers to toxicity class V (almost non-toxic pharmaceutical substance) …