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Molecular Medicine Peer-reviewed scientific journal

Found: 7

ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2025 · pp. 34–40

Efficacy of antitumor therapy schemes with carboplatin in an experimental model of lung carcinoma and drug-resistant tuberculosis

Introduction. Up to 20% of tuberculosis patients suffer from malignant neoplasms. In this case, the combination of both diseases in the lung is a particular problem. More than 60% of patients cannot complete combination therapy due to drug-resistant MBT. The a…

10.29296/24999490-2025-01-04Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2024 · pp. 21–28

BIOLOGICAL MODEL OF LUNG CANCER COMBINATION AND TUBERCULOSIS: DEVELOPMENT FOR PRECLINICAL STUDY OF RATIONAL COMBINATIONS OF TARGETED ANTITUMOR AND ANTITUBERCULOSIS THERAPY

Introduction. Lung cancer occupies a leading position in the structure of mortality from cancer. Chronic inflammation characteristic of tuberculosis increases the risk of lung cancer. Currently, more and more information is emerging confirming the cause-and-ef…

10.29296/24999490-2024-02-04Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2023 · pp. 25–32

THE EFFECT OF ANTITUMOR DRUGS ON THE COURSE OF TUBERCULOSIS IN THE EXPERIMENT

Introduction. Lung cancer and tuberculosis, make a significant affect to the morbidity and mortality of the population in Russia and in the world. Strategy of medication therapy has not been developed for cases when these diseases are combined. The aim of the …

10.29296/24999490-2023-02-04Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2023 · pp. 56–64

COMBINED EFFECT OF POLYPEPTIDE COMPLEXES ON THE DEVELOPMENT OF ORGANOTYPIC CULTURE OF RAT TISSUES

Introduction. The formation of effective bioregulators for the maintenance of the basic physiological functions, so as polypeptide complexes (PPCs), is one of the actual task of modern biology and medicine. Purpose of study. Effect of combination of polypeptid…

10.29296/24999490-2023-01-09Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2020

THE STATE OF THE PROTEOLYSIS SYSTEM IN PATIENTS WITH COMMUNITY-ACQUIRED PNEUMONIA ON THE BACKGROUND OF DIABETES MELLITUS TYPE 2

Introduction. The progression of inflammation in community-acquired pneumonia is associated with the activation of proteolytic enzymes, involved in eliminating the pathogenic agent, removing damaged structures. Proteinases are controlled by α1-proteinase inhib…

10.29296/24999490-2020-02-11Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2018

BONE AND MALIGNANT DISEASES OF UTERINE: PROFILE OF EXPRESSION OF GENES OF STEROID RECEPTORS AND TUMOR SUPPRESSOR PTEN

Introduction. Myoma occupies a leading place in the structure of gynecological diseases, reduces the fertility rate and living standardsin females of reproductive age. In 85% cases myoma is combined with adenomyosis, which complicates the treatment and increas…

10.29296/24999490-2018-03-08Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2017

GROWTH FACTORS AND PLASMINOGEN ACTIVATION SYSTEM IN TUMORS OF THE ORGANS OF THE FEMALE REPRODUCTIVE SYSTEM

Background. Plasminogen activators play the leading role in the tumor growth and metastasis. Growth factors stimulate proliferative processes and are involved in neoangiogenesis. Aim of the study. Identification of changes in components of the fibrinolysis sys…

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