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METHODICAL ASPECTS OF USING RAT RBL-2H3 BASOPHILS FOR DEGRANULATION STUDY

Goryacheva M.A., Kryshen K.L., Katelnikova A.E., Akulova E.G., Makarova M.N., Makarov V.G.

Introduction. Mediator release from mast cells or basophils is the key event in many acute allergic and inflammatory processes. Rat basophilic leukemia cell line RBL-2H3 cells is widely used as a model for studying mast cells degranulation. Aim of the study. T…