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Molecular Medicine Peer-reviewed scientific journal

Found: 6

ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2025 · pp. 24–29

Using claudin-2 to mark mossy fibers in the mouse hippocampus

The purpose of the present study was to test the possibility of identifying hippocampal mossy fiber projections by staining mouse brain sections with antibodies to the claudin-2 protein. Material and methods: the subjects of the study were 9 male wild mice. Se…

10.29296/24999490-2025-04-04Details ↗
ОБЗОР2023 · pp. 12–21

MOLECULAR MECHANISMS OF NEUROINFLAMMATION AND SLEEP DEPRIVATION IN THE DEVELOPMENT OF AGE-ASSOCIATED COGNITIVE DYSFUNCTION

Introduction. Proinflammatory cytokines produced in elevated concentrations in the elderly significantly impair neurogenesis in the dentate gyrus of the hippocampus, long-term potentiality, alter neuronal morphology and function, and increase apoptosis. This l…

10.29296/24999490-2023-03-02Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2018

PROTECTION OF NEURAL STEM CELLS FROM GENOTOXIC EFFECTS BY FACTORS SECRETED BY MESENCHYMAL STEM CELLS

Introduction. The brain injury induced during radiotherapy and chemotherapy is largely dependent on a disruption of neurogenesis in the subgranular zone of the dentate gyrus in the hippocampus as a result of the neural stem cells (NSCs) damage. The aim of the …

10.29296/24999490-2018-06-05Details ↗
ОБЗОР2017

WHY ADULT BRAIN NEEDS NEW NERVE CELLS?

A half century of studying the neurogenesis of the adult brain has produced much evidence for an endogenous conversion of neural stem cells. Yet the idea receives increasing criticism, in addition to the many positive comments. Does neurogenesis proceed at a r…

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