ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2026 · pp. 3–8
Khaspekov L.G., Mudarisova R.S., Kolotyeva N.A., Salmina A.B., Li W., Illarioshkin S.N.
Introduction. Parkinson’s disease (PD) is a chronic, progressive neurodegenerative disorder, the primary pathological feature of which is the death of dopaminergic neurons in the substantia nigra pars compacta and the accumulation of aggregated α-synuclein. Th…
ОБЗОР2019
Kuznik B.I., Davidov S.O., Chalisova N.I.
There are presented data about rejuvenating mesencephalic astrocyte-derived neurotrophic factor (MANF) and its physiological functions. This is a new neurotrophic factor, produced by the mesencephalic astrocytes and it is different from other factors by its ac…
ОБЗОР2018
Sapronova M.R., Shnayder N.A.
Modern methods of treatment of Parkinson's disease (PD) remain to be unsuccessful in cessation of the progression of neurodegenerative processes in the brain. The role of certain genes is proven by the etiology of PD, 10–15% of cases represent a monogenic dise…