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MOLECULAR-GENETIC CHARACTERISTICS OF EARLY RHEUMATOID ARTHRITIS

Guseva I. A., Demidova N. V., Soroka N.E., Luchikhina E. L., Lukina G. V., Fedorenko E.V., Aronova E. S., Samarkina E. Yu., Trofimov D. Yu., Karateev D. E., Nasonov E.L.

Objective. To study the distribution of PTPN22, TNFAIP3, CTLA4, TNFA, IL-6, IL-6R, IL-10, MCP-1, ICAM1 alleles and genotypes in early rheumatoid arthritis (eRA) patients and controls, and assess their value as potential molecular-genetic markers of predisposit…