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Molecular Medicine Peer-reviewed scientific journal

Found: 8

ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2025 · pp. 58–69

Polypragmasy in elderly and senile patients with chronic kidney disease: START/STOP criteria in elderly and senile patients taking DOAC

Introduction. Thanks to the achievements of modern medicine, it was possible to significantly increase the life expectancy of the population. Molecular mechanisms of aging include telomere shortening, DNA damage accumulation, mitochondrial dysfunction, leading…

10.29296/24999490-2025-05-07Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2025 · pp. 39–47

Ways to increase freedom from DOAC-dependent complications in elderly patients with polypharmacy and chronic kidney disease: molecular and genetic aspects

Introduction. Thanks to advances in modern medicine, it has been possible to significantly increase life expectancy. With the high effectiveness of methods for diagnosing and treating many chronic pathologies, a sharp increase in the number of elderly patients…

10.29296/24999490-2025-03-05Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2021

SALIVA CONCENTRATION OF SIRTUINS: PERSPECTIVES OF APPLICATION FOR CORONARY HEART DISEASE DIAGNOSTICS AND AGING RATE

The aim is the comparative analysis of saliva concentration of sirtuins, in middle age and elderly people without cardiovascular pathology (CP) and with coronary heart disease (CHD). Methods. Saliva was obtained from healthy donors (73 persons without CP, «nor…

10.29296/24999490-2021-06-06Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2018

SKIN FIBROBLASTS AS AN OBJECT FOR LIFE-TIME MOLECULAR DIAGNOSTIC OF THE ALZHEIMER DISEASE

Introduction. The Alzheimer disease (AD) is the socially important neurodegenerative disease. The promising way of the early lifetime diagnosis of the AD is the investigation of the expression of signal molecules by cells in a cerebrospinal fluid, blood lympho…

10.29296/24999490-2018-05-11Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2018

THE KED PEPTIDE REGULATES THE SYNTHESIS OF SIGNAL MOLECULES – MARKERS OF ADHESION AND REGULATORS OF TROMBOGENESIS IN INTACT AND DAMAGED VASCULAR ENDOTHELIUM

Introduction. The investigation of molecular and cellular mechanisms of atherosclerosis and the development of restenosis and the possibility of the regulation of these processes by short peptides opens new perspectives for the delivery of vasoprotective prepa…

10.29296/24999490-2018-01-10Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2017

AΒ42 – APROMISSING NON-INVASIVE MARKER FOR LIFE-TIME DIAGNOSIS OF ALZHEIMER’S DISEASE

Introduction. Alzheimer's disease (AD) is a socially important neurodegenerative disease. The prevalence rate of AD is increasing over recent years. According to the hypothesis concerning AD to be a systematic disease its manifestation can be detected in vario…

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