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Molecular Medicine
Found: 5
Aim of the study was to establish the significance of TR-receptor, P2X1-receptor and P2Y-receptor synergism for the efficiency of TC aggregation in patients with different sensitivity to non-selective NSAIDs, which will allow us to approach an understanding th…
The study aims to analyze the dependence of an α1А-adrenoreceptor antagonist effectiveness on G-protein-coupled receptors (GPCRs) intracellular signaling in the passage of medium-sized calculi from the ureter. Material and methods. The study was prospective an…
Аim of the study was to evaluate the activity of receptors that control contraction (α2-adrenergic receptor, purine P2X1 and P2Y receptors, angiotensin AT1 receptor, TxA2 receptor) and relaxation of smooth myocytes (adenosine A2 receptor) during standard litho…
The reasons for the low efficiency of the α1A-blockers using in the scheme of lithokinetic therapy (LCT) remain unclear. The aim of the study was to evaluate the activity of the purinergic P2X1 receptor in the blockade of the α1A-adrenergic receptor during LCT…
Introduction: Urate nephrolithiasis is a common form of urolithiasis. The development of new methods for pharmacological correction of this disorder requires their practical laboratory assessment. So far, it is necessary to determine the most typical biochemic…