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REGULATORY HIF CASCADE IN EPIDERMAL KERATINOCYTES: DYNAMICS OF ACTIVITY AND DEPENDENCE ON HYPOXIA

Panteleyev A.A., Usakin L.A., Solovieva E.V., Paltsev M.A.

Introduction. The transcriptional activity of hypoxia-inducible factor 1 (HIF1) not only drives cellular adaptation to O2 deficiency, but also plays an important role in the development and functioning of various organs and tissues. Data on the role of HIF reg…