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Molecular Medicine Peer-reviewed scientific journal

Found: 8

ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2018

THE ROLE OF STEROID ER, AR RECEPTORS, BRN-3Α AND TRIM16 NUCLEAR TRANSCRIPTION FACTORS IN THE DEVELOPMENT OF KIDNEY CANCER

Introduction. The study of molecular mechanisms of the development of kidney cancer is one of the actual problems in oncology. There is conflicting information about the importance of steroid hormone receptors in the kidney cancer. The aim of the study was to …

10.29296/24999490-2018-05-10Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2018

BONE AND MALIGNANT DISEASES OF UTERINE: PROFILE OF EXPRESSION OF GENES OF STEROID RECEPTORS AND TUMOR SUPPRESSOR PTEN

Introduction. Myoma occupies a leading place in the structure of gynecological diseases, reduces the fertility rate and living standardsin females of reproductive age. In 85% cases myoma is combined with adenomyosis, which complicates the treatment and increas…

10.29296/24999490-2018-03-08Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2018

PROGESTER ONERECEPTION IN THE PERIPHERAL BLOOD MONONUCLEAR CELLS AND THE SUCCESS OF ASSISTED REPRODUCTIVE TECHNOLOGY

Introduction. Low rate of the pregnancy frequency in the IVF programs is one of the challenges in gynaecology nowadays. One of the approaches to enhance the efficacy of the assisted reproductive technology is to estimate the success of the forthcoming procedur…

10.29296/24999490-2018-01-11Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2017

EXPRESSION OF ESTROGEN RECEPTORS IN BREAST AS MOLECULAR MARKERS OF PROLIFERATION PROGRESSION

Introduction. Fibroadenomatosis (FAM) is a heterogeneous group of pathological conditions of the mo-Nochnoi gland, with hormone-dependent nature and different degree of risk maligni of the organization. The use of routine histological stains is not enough to d…

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Research article2014

FEATURES OF EXPRESSION OF SEX STEROID HORMONES RECEPTORS IN PELVIC ENDOMETRIOSIS

Introduction. Changes of steroid hormone receptors take an important place in the pathogenesis of endoemtriosis. Literature data about estrogen receptor-alpha (ERα) in this disease is contradictory. The aim of our study was to determine the expression of ERα a…

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Research article2014

ENDOMETRIUM: FROM NUCLEAR RECEPTORS TO TEST MODELS OF NEW DRUGS

Introduction. Endocrine factors are considered to be important in the etiology of spontaneous abortion. Aim of the study. Histological and immunohistochemical characterization of the expression of estrogen and progesterone receptors in the gravid endometrium d…

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Research article2014

THE ASSOCIATION OF PROTEASOME ACTIVITY AND SUBUNITS COMPOSITION WITH ESTROGEN AND PROGESTERONE RECEPTORS EXPRESSION IN BREAST АND ENDOMETRIAL CANCERS

Introduction. The features of pathogenesis of main tumors of the female reproductive system are determined by the impact of estrogen on target tissues. In this connection there appears the need to study the regulation of estrogen and progesterone receptors in …

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