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GALECTIN-1 INDUCES MITOCHONDRIAL APOPTOTIC PATHWAY IN CD4+ T-CELLS

Yakushina V.D., Vasileva O.A., Ryazantseva N.V., Novitsky V.V., Starikova E.G., Tashireva L.A., Nebesnaya I.S.

Introduction. Galectin-1 binds to cell surface glycoprotein and participates in cooperation of immune cells. It is supposed that the CD4+- lymphocytes can be target for immunosuppressive activity of galectin-1. However, there is no sufficient information about…